The wet lab was started in April 2015. Besides the lab head, one experimental PhD student and several theoretically trained PhD students and Post-Docs are currently working in the lab; future expansions are planned. The group focuses on image-based modelling and simulation of mouse organogenesis. We use transgenic mouse lines with fluorescent tissue markers to image developing embryonic mouse organs in 2D and 3D cultures with a view to understand the developmental principles that control the growth and differentiation processes. A state-of-the art imaging centre with access to confocal microscopy and light-sheet microscopy, a single cell facility, and a quantitative genomics facility are available in-house.
The successful applicant must be able lead the experimental part of the group and should therefore have several years of Post-Doc experience. In particular, the lab head is responsible for all animal license applications for the group in collaboration with the ETH animal facility. Accordingly, applicants must be experienced in working with transgenic mice and must hold or be able to apply for the required licenses and permits to work with mice. The ideal candidate has experience with mouse organ cultures, organoids, stem-cell based tissue engineering approaches, and imaging techniques. Applicants should be enthusiastic to do research at the interphase of developmental and computational biology. The position provides an opportunity to learn about image analysis, bioinformatics, and mathematical modelling; prior knowledge in these fields is not required.
The Department of Biosystems Science and Engineering (D-BSSE) of ETH Zurich is located in Basel, a European hotspot for biomedical research, in close proximity of the Biozentrum and Department of Biomedicine of the University of Basel, the Friedrich Miescher Institute for Biomedical Research, and the pharmaceutical and biotech industry. ETH Zurich is a major research university, offering an excellent environment for innovative and collaborative research across disciplines.