The Paul Scherrer Institute PSI is the largest research institute for natural and engineering sciences within Switzerland. We perform cutting-edge research in the fields of matter and materials, energy and environment and human health. By performing fundamental and applied research, we work on sustainable solutions for major challenges facing society, science and economy. PSI is committed to the training of future generations. Therefore, about one quarter of our staff are post-docs, post-graduates or apprentices. Altogether, PSI employs 2100 people.

For the Structural Biology of Neuronal Systems group we are looking for a
PhD Student
Your tasks
  • X-ray imaging, biophysical and biochemical characterization of in vitro amplified αSyn aggregates
  • Build a new animal model with patient-derived αSyn strains
  • Determine the Parkinson Disease PD- like behavior and biochemical indexes of the positive animal groups
  • Develop a multimodal technique with SLS beamline scientists for the X-ray tomography data col-lection and analysis
  • Take on night shifts in helping with sample preparation and data collection
  • Participate in collaborative research of the PET-CT and light-sheet fluorescence imaging with ex-ternal collaborators
  • Co-supervise and co-support master students
  • Present work at international conferences / workshops and publish work
Your profile
  • High interest and motivation to work on an interdisciplinary subject
  • Practical experience in experimental work with neurodegeneration, animal model, amyloid pro-teins, X-ray tomography, electron microscopy or/and immunohistology will be considered as an asset
  • Good level of English as working language in spoken and written form is mandatory
  • Knowledge of German or willingness to quickly learn German is a plus
We offer
Our institution is based on an interdisciplinary, innovative and dynamic collaboration. You will profit from a systematic training on the job, in addition to personal development possibilities and our pronounced vocational training culture. If you wish to optimally combine work and family life or other personal interests, we are able to support you with our modern employment conditions and the on-site infrastructure.

For further information, please contact Dr Jinghui Luo, phone +41 56 310 47 64.

Please submit your application online by 15 February 2022 (including addresses of referees) for the position as a/an PhD Student (index no. 2413-00).

Paul Scherrer Institut, Human Resources Management, Silja Giacomini-Diebold, 5232 Villigen PSI, Switzerland