To reinforce our team in Geneva, Switzerland, and in Grenoble, France, we are seeking a PhD in glycobioinformatics.
PhD in glycobioinformatics in Geneva and Grenoble

Firm

University of Geneva (UNIGE)


Category

SIB


Work city

Geneva, Switzerland


Employment fraction

100%


Type of contract

temporary

Job tasks
PhD co-supervised by the University of Grenoble Alpes (France) and the Proteome Informatics Group (PIG) in Geneva. The main subject is the study of lectins. It is multidisciplinary and encompasses Structural Biology, Chemistry and Computer Science.

Lectins are proteins that interact non-covalently with carbohydrates reversibly and specifically while displaying no catalytic or immunological activity. Lectins are thought to have the ability to decipher the glycocode, i.e., the structural information present on complex carbohydrates at the cell surface. Lectins are involved in many biological processes, their interactions with carbohydrates often play an essential role to the onset, detection, and potentially prevention of human diseases such as cancer, inflammation, diabetes, neurodegenerative diseases and bacterial and viral infections.

We propose to gather the knowledge about lectins to give new dimensions to the lectin3D database (http://glyco3d.cermav.cnrs.fr) and to develop new tools for characterising and annotating lectins.The first step will be to elaborate a lectin classification from different perspectives. The second step will be to propose tools for correct annotation of lectins in newly sequenced genomes, lectins especially in fungal, algi, invertebrates and bacterial species. Finally, this approach will be applied on a selection of genomes.


Work place
 
18 months in Geneva, 18 months in Grenoble
Profile requirements
  • hold a master or engineering degree or any equivalent qualifications,
  • very good programming skills applied in bioinformatics (preference for Java and Python),
  • good knowledge of database development and management (PostgreSQL),
  • some background in data analysis and mining methods,
  • experience in JavaScript is a plus,
  • good language skills in English both orally and in writing.
How to apply
If you are interested in this challenging and highly interesting position, please send your application including CV and letter of motivation to:

Frédérique Lisacek (frederique.lisacek@sib.swiss)
Phone number : +41 22 379 50 50